<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y   K103N, Y181C, G190A V179F, Y318F S3G, E28K, K32E, V35M, K43E, E44A, K101R, V111I, K122E, I135V, T139K, I167V, T200A, E203D, H208Y, R211T, L228H, V245E, A272P, L283I, R284K, I293V, E297K, E300D, M357T, A376S, T386I, K390R, Q394L, E399D  
>178038| codons 1-399
PIGPIETVPVKLKPGMDGPKVKQWPLTKEKIEALMEICTELEEAGKISKIGPENPYNTPV
FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLRKNKSVTVLDIGDAYFSVPL
DEDFRKYTAFTIPSVNNEKPGIRYQYNVLPQGWKGSPAIFQSSMTKVLEPFRKQNPDIFI
CQYVDDLYVASDLEIGQHRAKIDELRQYLWTWGFYTPDKKHQKEPPFHWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIKGTKALTEVVPLTKEAD
LELAENREILKEPVHGVFYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTRGA
HTNDVKQLTEAVQKISTESIVIWGKIPKFRLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I50V, I54V, V82A, L90M L23I, L33F, K43T, F53L, T74P L10I, I13V, K20R, E35N, M36I, N37NI, K55R, R57K, Q61N, I62V, L63P, L89I  
>178038| codons 1-99
PQITLWQRPIVTVKIGGQLREAILDTGADDTVFENIILPGRWTPKIIGGVGGLVRVKQYD
NVPIEICGHKAIGPVLVGPTPANIIGRNIMTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012