<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L210W, T215Y N348I Y181C   T39K, K43E, K49R, T69N, I135T, T200AE, E203K, H208Y, R211K, K223E, L228R, V245I, K277R, L283I, I293V, E312EA, D324E, Q334A, I341F, R356K, M357V, G359S, K366R, T386I, A400T V111VIM
>177873| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICKELEEEGKISRIGPENPYNTPV
FAIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDMGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYMDDLYVGSDLEIGQHREKIKELRQYLWKWGFYTPDKKHQEEPPFRWMGYELHPDKWT
VQPIILPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLIRGTKALTEVVPLTEEAE
LELAENREILKAPVHGVYYDPSKELIAEIQKQGAGQWTYQFYQEPFKILKTGKYAKVRSA
HTNDVRQLTEAVQKIATESIVIWGKIPKFKLPIQKETWET

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, I84V, L90M V11IL, Q58QE, L89V Q7QH, L10I, I13V, K20T, R57RK, I62V, L63P, A71V, I72R, G73GD, T91S, Q92K  
>177873| codons 1-99
PQITLWHRPILTVKIGGQLTEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFVKVKEYD
QVPIEICGHKVRDTVLVGPTPVNVIGRNVMSKIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012