<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V, L210W, T215Y K219E K101E, Y181C, G190A V108VI P4PS, T7P, K20R, V35VIM, S68SG, K122P, I135T, D177E, V245K, S251I, I293V, P294Q, E297R, K311R, R356K, G359GS, K366R, T386I  
>177625| codons 1-400
PISSIEPVPVKLKPGMDGPRVKQWPLTEEKIKALMEICTEMEKEGKISKIGPENPYNTPV
FAIKKKNGTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTILDVGDAYFSVPL
DPDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI
CQYVDDLYVASDLEIGQHRTKIEELRQHLWRWGFYTPDEKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKDIWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVQLTREAE
LELAENREILREPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDVRQLTEAVQKIATESIVIWGKIPKFKLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46LV, I47V, I54L, I84V, L90M L33F, Q58E, G73S L10IV, T12TS, I13V, K14R, G16A, R57K, D60E, L63P, A71V, I72V, V77VI, P79S, I93L  
>177625| codons 1-99
PQITLWQRPVVSVRIAGQLKEALLDTGADDTIFEEMNLPGRWKPKVVGGIGGFLKVKEYE
QIPIEICGHKVVSTVLIGSTPVNVIGRNLMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012