<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, M184V, T215Y N348I L100I, K103N Y318YF V35R, T39A, K122E, I135T, I142V, S162Y, T200A, L228R, A272P, K281R, P294T, E297K, I326V, I329L, M357T, A376S, K390R, Q394L, E399D  
>176839| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALREICAELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRAKIEELRQHLLRWGFYTPDKKHQKEPPFRWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTEVITLTKEAE
LELAENREILKEPVHGVFYDPSKDLVAELQKQGQGQWTYQIYQEPFKILKTGKYARTRGA
HTNDVKQLTEAVQKISTESIVIWGKTPKFRLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, T12IKN, I15V, G16E, E35D, M36I, R41K, R57K, Q61DN, L63LV, I72T, I93L  
>176839| codons 1-99
PQITLWQRPVVNIKVEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
NIVIEICGHKATGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012