<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67DN, L74LI, M184V, T215Y     A98G V21I, K43E, E44A, D123E, I135L, S162C, Q174QKR, E203EG, Q207E, H208Y, R211K, I257L, A272P, K281R, I293V, E297K, K311R, D324E, G333E, Q334L, G359GS, A360T, T386TI, K390R  
>176191| codons 1-399
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALVEICTELEEAGKISKIGPENPYNTPV
FAIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKRNPDIVI
YQYVDDLYVGSDLEIGQHRTKIGELREYLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDLQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTEVVPLTKEAE
LELAENREILREPVHGVYYDPSKELIAEIQKQELGQWTYQIYQEPFKNLKTGKYARMRST
HTNDVKQLTEAVQKIATESIVIWGKIPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    E35D, M36I, N37D, P39PT, L63P, H69N, A71V, I72V, V77I, I93L  
>176191| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDIDLTGRWKPKMIGGIGGFIKVRQYD
QIPIEICGNKVVGTVLIGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012