<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, T215F K219E Y181C, G190A   V35M, T39A, K43KR, W88C, K101Q, V118VI, D123E, R172RK, D177E, L228H, V245K, A272P, T286S, A288T, V292VI, I293V, E297K, R356RK, M357MI, R358RK, G359GS, T386IV, K390R  
>175850| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICAEMEREGKISKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFCEVQLGIPHPAGLQKKKSVTVLDVGDAYFSIPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPEIVI
CQYMDDLYVASDLEIGQHRTKIEELRQHLLRWGFFTPDEKHQKEPPFHWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGSKTLTEIVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKIKSA
HTNDVKQLTEAVQKIATESIVIWGKVPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, I47V, G48V, I54M, V82T L33F L10V, K20R, E34EQ, E35D, M36I, R41K, K55KR, R57K, Q61D, C67E, A71V, I72T, T74S, I93L  
>175850| codons 1-99
PQITLWQRPVVTIKIGGQLREALLDTGADDTIFQDINLPGKWKPKMVVGIGGFMRVKQYD
DILIEIEGHKVTGSVLVGPTPTNIIGRNLLTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012