<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L210W, T215Y N348I     V35T, T39M, K43E, K101R, I135T, S162Y, E169D, L228R, A272P, K281KR, T286P, I293V, E297K, I326IV, F346C, M357MT, A376S, T377TI, Q394L  
>175339| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICMELEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLRKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILDPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRTKIEELRQHLWRWGFYTPDKKHQKEPPFRWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGPKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGQGQWTYQIYQEPCKILKTGKYARTRGA
HTNDVKQLTEAVQKISIESIVIWGKTPKFKLPILKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M L33I L10V, I13V, K14R, K20R, E35D, M36I, N37D, R57K, Q61N, I62V, L63P, T74S, Q92K, I93L  
>175339| codons 1-99
PQITLWQRPVVTVRIGGQLREALLDTGADDTVIEDIDLPGRWKPKMIGGIGGFIKVKQYD
NVPIEICGHKAIGSVLVGPTPVNIIGRNLMTKLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012