<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, L210*SW, T215FY   K101E, Y181C, G190S   V35T, V90I, K122E, I135V, I178M, T200A, R211RK, K223Q, L228R, V245K, A272P, L283I, T286A, I293V, E297K, R356K, G359S, A371V, A376C, Q394L, K395R, E399D  
>170892| codons 2-399
ISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEIQLGIPHPAGLEKKKSVTVLDVGDAYFSVPLD
EDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVIC
QYMDDLYVSSDLEIGQHRAKIEELRQHLWKWGFYTPDKKHQQEPPFRWMGYELHPDKWTV
QPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGAKALTEVVPLTKEAEL
ELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMRSAH
TNDVKQLTEVVQKICTESIVIWGKTPKFKLPILRETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82S, L90M L33F, K43T, G73S L10I, I15V, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, Q61D, L63P, A71V, I72T, I85V, I93L  
>170892| codons 1-99
PQITLWQRPIVTIKVGGQLREALLDTGADDTVFEDIELPGKWTPKIIGGIGGFVRVKQYD
DIPIEICGHKVTSTVLVGPTPSNIVGRNLMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012