<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215Y N348I Y181C   K32I, V35T, V90VI, I135V, S162A, E203K, R211S, A272P, V276I, T286A, A288AT, E297K, S322SA, P345Q, M357T, K366R, A376S, K390R, Q394L, E399D  
>170506| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIIALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPDIVI
CQYVDDLYVGSDLEIGQHRTKIKELRQHLLSWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLLRGAKTLTEVIPLTKEAE
LELAENREILKEPVHGVYYDPAKDLIAEIQKQGQGQWTYQIYQEQFKILKTGKYARTRGA
HTNDVRQLTEAVQKISTESIVIWGKTPKFRLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13IV, K14KEIV, I15V, K20R, E35D, M36I, R41K, R57K, D60E, Q61D, E65EK  
>170506| codons 1-99
PQITLWQRPLVTVVVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYE
DILIKICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012