<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, T215Y   L100I, K103N, Y181YC   V35T, V60I, K101KQ, K102KR, I135V, Q207QE, L228R, A272P, K281R, T286P, E291D, E297K, S322T, D324E, A376S, Q394L, K395R, E399D  
>170453| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGIQRNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYMDDLYVGSDLEIGQHRTKIEELREHLLRWGFYTPDKKHQKEPPFRWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGPKALTDVIPLTKEAE
LELAENREILKEPVHGVYYDPTKELIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA
HTNDVKQLTEAVQKISTESIVIWGKTPKFKLPILRETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A Q58E L10IV, I15V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, H69Y, I72T  
>170453| codons 1-99
PQITLWQRPVVTIKVEGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVKEYD
NILIEICGYKATGTVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012