<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, Y115F, M184V T215V Y181C   P1L, I50IM, T69TA, E79D, R83K, V90I, K101R, S162Y, V179I, R211K, F214L, E224D, L228R, V245E, I293V, E297V, I329V, Q334L, R358K, G359S, A371I, K390R F77IT, F87FS, L109LR
>167152| codons 1-400
LISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKMGPENPYNTPV
FAIKKKDSAKWRKVVDTRDLNKKTQDSWEIQLGIPHPAGLRKKKSVTVRDVGDAFFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIII
CQYVDDLYVGSDLEIGQHRTKIEELRQHLLKWGLVTPDKKHQKDPPFRWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTVEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGLGQWTYQIYQEPFKNLKTGKYARMKSA
HTNDVKQLTEIVQKIATESIVIWGKTPKFRLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47V, I54V, V82S, L90M L33F, F53L, L89V L10I, I13V, L19LV, K20T, E35D, M36I, N37D, R57K, I62V, L63P, I66F, A71V, T91S, Q92R  
>167152| codons 1-99
PQITLWQRPIVTVKIGGQVTEALLDTGADDTVFEDIDLPGRWKPKIVGGIGGLVKVKQYD
QVPIEFCGHKVIGTVLVGPTPSNIIGRNVMSRIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012