<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, T215Y       V35T, K49KR, D123E, I135V, K166KR, V179I, T200TK, Q207E, K223KE, V261I, A272P, V276I, T286A, I293V, P294A, E297K, N348T, A376T, Q394L  
>166492| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIII
YQYVDDLYVGSDLEIGQHRKKIEELREHLLRWGFYTPDKKHQEEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLIGKLNWASQIYPGIKIKQLCKLLRGAKALTEVVALTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKTLKTGKYARMRGA
HTNDVKQLTEAVQKITTESIVIWGKTPKFKLPILKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N, M46L N88D I15V, L19LQ, K20T, E35D, M36I, R41K, R57K, Q61N, I64IV, E65D, A71V, I72T  
>166492| codons 1-99
PQITLWQRPLVTIKVGGQQTEALLDTGADNTVLEDINLPGKWKPKLIGGIGGFIKVKQYD
NILVDICGHKVTGTVLVGPTPVNIIGRDLLTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012