<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, Q151M, M184V, T215FV A62AV, V75I, F116Y, K219Q L100I, K103N   K20R, E28A, S48T, T69N, K101Q, K122E, I135T, G196R, I202V, R211Q, V245M, A288S, E300ED, M357T, R358K, A376T, K385R, T386I, K388KR, K390R, E399D  
>165823| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTAEKIKALVEICTEMEKEGKITKIGPENPYNTPV
FVIKKKNSNRWRKLIDFRELNKRTQDFWEVQLGIPHPAGIQKNKSVTVLDVGDAYYSVPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIRQHRTKVEELRQHLLQWGFVTPDQKHQKEPPFLWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKSLTEVIPLTEEAD
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTKGA
HTNDVKQLTEAVQKITTESIVIWGRIPRFRLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, V82T L10F T12K, I15V, G16E, L19I, K55R, L63C, I64V, T74A, V77I, I85V  
>165823| codons 1-99
PQITLWQRPFVKIKVEGQIKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIRVRQYD
QICVEICGHKAIGAVLIGPTPTNIVGRNLLTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012