<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, T215Y   K101P, K103S, G190A   E28K, K32E, V35I, V60I, S68G, K122E, D123DE, I135T, I142T, V179I, T200I, A272P, Q278H, L283I, E297T, Q334R, R356K, T377R, T386I, K390R, Q394L  
>165635| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALIEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDGTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLPKSKSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSTNNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII
YQYMDDLYVASDLEIGQHRIKIEELRQHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLIRGTKALTEVIPLTTEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGRGQWTYQIYQEPFKNLKTGKYAKMRGA
HTNDVKQLTEAVQKIARESIVIWGKIPKFRLPILKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A   L10I, I15L, L19V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63S  
>165635| codons 1-99
PQITLWQRPIVTIKLGGQVREALLDTGADDTVLEDINLPGKWKPKIIGGIGGFVRVKQYD
NVSIEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012