<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, I84V, L90M L23I, Q58E L10I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63C, I64V, A71V, V77I, I93L  
>162645| codons 1-99
PQITLWQRPIVTIKIGGQLREAILDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVKEYE
NVCVEICGHKVIGTVLIGPTPANVIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67~, K70R, M184V, T215F T69G, K219E K103N V108I, L234I K20R, V35T, T39A, V60I, V90VI, K122KE, I135V, V179VI, D218E, L228H, A272P, K281R, P294S, E297R, E300ED, Q334H, V365I, Q367L, T369A, K374R, A376T, T386A, I393V, Q394L, T397A, E399D E291EG, N306ND
>162645| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICAELEKEGKISKIGPENPYNTPI
FAIKKK~SGRWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKNKSVTILDVGDAYFSVPL
DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII
YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFFTPEEKHQKEPPFHWMGYEIHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTGVISLTREAD
LELAEDREILKEPVHGVYYDPSKDLIAEIQKQGHGQWTYQIYQEPFKNLKTGKYARMRGA
HTNDIKLLAEAVQRITTESIVIWGKAPKFKLPVLKEAWD

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012