<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74I, Y115F, M184V, T215Y K219Q G190A   S3C, T27S, V35T, T39M, V118VI, D123E, I135T, E138A, I167V, R172K, D177E, I178L, V179T, R211RG, D218E, A272P, V276I, Q278E, K281R, L283I, I293V, E297R, Q334Y, R356K, K390R, Q394L K101D
>162512| codons 2-400
ICPIETVPVKLKPGMDGPKVKQWPLSEEKIKALTEICMELEKEGKISKIGPENPYNTPVF
AIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLDKKKSVTVLDVGDAFFSIPLD
KEFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKVLEPFKKQNPELTIY
QYVDDLYVASDLEIGQHRTKIEELRQHLLGWGFYTPEQKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKIKELCRLIRGTKALTEVVPLTREAEL
ELAENREILKEPVHGVYYDPSKDLIAEIQKQGYGQWTYQIYQEPFKNLKTGKYAKMRGAH
TNDVKQLTEAVQKIATESIVIWGKTPKFRLPILKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82S, I84V   L10LV, I15V, G16E, K20R, E34A, E35D, M36I, R41K, K43I, K55R, R57K, D60DN, Q61DN, L63C, L89LM  
>162512| codons 1-99
PQITLWQRPVVTIKVEGQLREALLDTGADDTVLADINLPGKWIPKIIGGIGGFVRVKQYN
NICIEICGHKAIGTVLVGPTPSNVIGRNMLTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012