<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, M184V, L210W, T215Y K219N Y181C, G190S K101H, F227L K20R, V35L, T39A, K43Q, E44D, K49R, S68G, V118I, K122KPQT, D123DE, I135V, E138ED, S162C, K173T, Q174K, V179IT, I195L, G196E, T200A, E203K, Q207QE, R211K, K223Q, L228HR, A272P, E297R, I329L, R358K, G359S, A376S, T386I, K390R, E399D  
>162123| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALLEICAELEQDGKISRIGPENPYNTPV
FAIKKKDGTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLHKKKSVTVLDVGDAYFSIPL
DTEFRKYTAFTIPSVNNDTPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRTKNPDITI
CQYVDDLYVSSDLELEQHRAKIKELREHLWKWGFYTPDNKHQQEPPLRWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTREAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGQGQWTYQIYQEPFKNLKTGKYARMKSA
HTNDVKQLTEAVQKISTESIVIWGKIPKFRLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A, L90M Q58E L10V, I15V, K20R, E35D, M36I, N37ND, R41RK, K55R, R57K, D60E, Q61N, I62V, L63P, A71V, I72V, L89M, I93L  
>162123| codons 1-99
PQITLWQRPVVTIKVGGQLREALLDTGADDTVLEDIDLPGKWKPKIIGGIGGFVRVKEYE
NVPIEICGHKVVGTVVVGPTPANIIGRNMMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012