<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L74LI, M184V, T215F K219E L100I, K103N   V35T, T39M, V60I, T69N, K122KE, D177N, Q197P, T200TA, I202IV, E203EK, Q207D, H208Y, R211K, D218DE, E224ED, L228H, V245E, A272P, I293L, E297R, D324E, I329L, Q334C, M357T, K390R, E399D  
>161920| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICMELEKEGKISKIGPENPYNTPI
FAIKKKNSNRWRKIVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPNIVI
YQYVDDLYVGSDLEIGPHRAKVKELRDYLLKWGFFTPEEKHQKDPPFHWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVLPLTREAE
LELAENREILKEPVHGVYYDPSKELIAELQKQGCGQWTYQIYQEPFKNLKTGKYARTRGA
HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54IM, V82A, I84IV L24I, L33F, F53L I3V, L10I, T12K, I15V, L19I, K20R, E35D, M36I, R41K, K43I, R57K, Q61N, L63P, A71V, I72IT, I93L I13S
>161920| codons 1-99
PQVTLWQRPIVKSKVGGQIREALIDTGADDTVFEDINLPGKWIPKIIGGIGGLMKVKQYD
NIPIEICGHKVTGTVLVGPTPANVIGRNLLTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012