<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L210W, T215Y A62V, V75I K103N, Y181C A98G K20R, V35T, T39K, K43E, W88WC, V118VI, K122E, I135T, I142V, I202V, E203K, Q207E, K223E, L228R, A272P, E297K, I329L, M357MT, R358K, K366R, A376T, I382IT, T386M, E399D  
>161316| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICKELEEEGKISKIGPENPYNTPV
FVIKKKDSTKWRKLIDFRELNKRTQDFCEVQLGIPHPGGLKKNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYMDDLYVGSDLEIGQHRTKVKELREHLWRWGFYTPDKKHQEEPPFRWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGQGQWTYQIYQEPFKNLKTGKYARTKGA
HTNDVRQLTEAVQKITTESIVTWGKMPKFKLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, L90M N88D L10V, I13V, I15V, Q18LM, L19I, K20T, E35N, M36I, R41K, K55R, R57K, Q61D, L63P  
>161316| codons 1-99
PQITLWQRPVVTVKVGGMITEALLDTGADDTVLENINLPGKWKPKIIGGIGGFIRVKQYD
DIPIEICGHKAIGTVLVGPTPVNIIGRDLMTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012