<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M G73S I15V, K20T, E35D, M36I, N37D, R41K, K45R, R57K, Q61N, L63P, I93L  
>161315| codons 2-99
QITLWQRPLVTIKVGGQLTEALLDTGADDTVLEDIDLPGKWKPRMIGGIGGFIKVKQYDN
IPIEICGHKAISTVLVGPTPVNIIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L T215L Y181I   V35T, T39M, S68G, D123E, I135V, T139R, I178IM, V179I, D250DG, A272P, K281R, T286A, I293V, E297K, P313PS, Y339F, M357MV, V365I, V381I, T386I, K390R, Q394L, E399D  
>161315| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICMELEKEGKISKIGPENPYNTPV
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSVNNERPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMII
IQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFLTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKGSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTEVVPLTKEAE
LELAENREILKESVHGVYYDPSKDLIAEIQKQGQGQWTFQIYQEPFKNLKTGKYARVRGA
HTNDIKQLTEAVQKIATESIIIWGKIPKFRLPILKETWD

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012