<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L74V, L210W, T215Y   V106M, M230L F227L V35I, T39K, K43E, E44D, V118I, D121H, K122E, I135T, S162D, K166R, I178L, E203D, H208Y, R211K, W212C, H221Y, A272P, L283I, R284K, I293V, I326V, K350R, R356K, G359A, T386I, K390R D76DN, P140T
>160464| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICKELEEDGKISKIGPENPYNTPV
FAIKKKNSDKWRKVVNFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSIPL
HEDFRKYTAFTIPSTNNETTGIRYQYNVLPQGWKGSPAIFQDSMTRILEPFRKQNPDLVI
YQYMDDLYVGSDLEIGQHRTKIDELRQYLWKCGFYTPDKKYQKEPPLLWLGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIKGTKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGQGQWTYQIYQEPFKNLRTGKYAKMRAA
HTNDVKQLTEAVQKIATESIVIWGKIPKFRLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I54IV, V82VA, L90M Q58QE L10I, T12K, L19I, N37C, R41K, L63P, A71V, I93L  
>160464| codons 1-99
PQITLWQRPIVKIKIGGQIKEALLDTGADDTVLEEMCLPGKWKPKMIVGIGGFVKVREYD
QIPIEICGHKVIGTVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012