<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
160444 160444 Argentina 2004 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54IV L10F, F53FL I13V, E35D, M36I, N37D, R41K, L63V, H69K, K70R, T74A, L89M, T91V  
>160444| codons 1-99
PQITLWQRPFVTVKIGGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGLVKVRQYD
QIVIEICGKRAIGAVLVGPTPVNIIGRNMLVQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V N348NI     T27TP, V35T, T39N, D121H, K122E, I135T, S162SN, E169D, Q174K, D177E, T200A, Q207E, R211K, V245K, K277R, T286A, E291D, V292I, I293V, E297K, A304E, E312D, I329L, G335D, R356K, M357R, R358K, G359S, A360AT, T377M, K390R, Q394H, A400T E29EK, E89EK
>160444| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLPEKKIKALTEICNEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWKVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILDPFRKKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVPLTKEAE
LELEENREILKDPVHGVYYDPSKDLIAELQKQGQDQWTYQIYQEPFKILKTGKYAKRKST
HTNDVKQLTEAVQKIAMESIVIWGKTPKFRLPIHKETWET

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012