<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74I   K103N A98G, P225H V35T, K46Q, V60I, K122E, I135L, E138G, K173KR, A272P, T286A, P294S, E297K, S322SA, I329L, V365I, T386I, K388KR, K390R  
>159510| codons 1-398
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGQISKIGPENPYNTPI
FAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSLNNGTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRQNPDIVI
YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEHPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVISLTKEAE
LELAENREILKEPVHGVYYDPAKDLIAELQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA
HTNDIKQLTEAVQKIATESIVIWGKIPRFRLPIQKETW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, L90M K43T L10I, I15V, G16E, K20M, E35D, M36I, R41R_R, R57K, Q61N, I62L, L63C, A71T, I72T, T74S, I85V  
>159510| codons 1-99
PQITLWQRPIVTIKVEGQLMEALLDTGADDTVLEDINLPGRWTPKMIGGIGGFVKVKQYD
NLCIEICGHKTTGSVLVGPTPANIVGRNLMTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012