<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, K70KNRS, L74LV, M184V, T215Y V75M K103N, Y181C   P1L, V35I, K43KR, K46R, K64KR, A98AS, S105A, V118I, K122E, D123DE, I135T, T139R, S162SG, V179I, V189VI, G196E, R211Q, F214L, V245E, K249KR, T286A, E297A, V317A, S322T, G335GCDY, R356RK, M357KT, A400T  
>159242| codons 1-400
LISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEREGRISKIGPENPYNTPV
FAIRKKNSTSWRKVMDFRELNKRTQDFWEVQLGIPHPSGLKKNKAVTVLDVGDAYFSIPL
DEEFRKYTAFTIPSTNNERPGIRYQYNVLPQGWKGSPAIFQGSMTKILEPFRKQNPDIII
CQYVDDLYIGSDLEIEQHRTKIEELRQHLLQWGLYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPERDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVIPLTAEAE
LELAENREILKEPVHGAYYDPTKDLIAEIQKQGQYQWTYQIYQEPFKNLKTGKYAKTRGA
HTNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWET

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, L90M L10FI, L33F, G73S, L89V I13V, K20V, E35G, M36I, N37D, R41K, I62V, L63P, I93L  
>159242| codons 1-99
PQITLWQRPIVTVKIGGQLVEALLDTGADDTVFEGIDLPGKWKPKLIGGIGGFIKVRQYD
QVPIEICGHKAISTVLVGPTPVNIIGRNVMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012