<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, M184V, T215F   L100I, K103N A98G K20R, V35VI, K43Q, V118I, K122E, T165I, K173Q, Q174K, D177E, I178L, Q197L, R211K, F214L, H221Y, L228LR, A272P, I293V, P313Q, Q334L, M357T, R358K, A376S, T377L, K390R, K395R  
>158832| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTELEQEGKISKIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPGGIKKNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRQKNPELVI
YQYVDDLYVGSDLEIGLHRTKIEELRQHLLKWGLFTPDKKYQKEPPFRWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE
LELAENREILKEQVHGVYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKYARTKGA
HTNDVKQLTEAVQKISLESIVIWGKTPKFRLPIQRETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, V82T, I84V L24I L10I, I15IV, K20IM, K43R, L63P, I64V, I66IV, A71V, V77I, I93L  
>158832| codons 1-99
PQITLWQRPIVTIKVGGQLMEALIDTGADDTVLEEMNLPGRWRPKIIGGIGGFIKVRQYD
QIPVEVCGHKVIGTVLIGPTPTNVIGRNLLTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012