<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T215FLPS K219Q, N348I Y181V   V35T, T39E, V60I, T69TN, W88C, K122E, I135V, I142V, I202V, Q207E, F214L, L228H, A272P, K281R, T286A, P294S, E297K, I341IV, I375V, T377TI, T386TI, K390KR, Q394L, E399D  
>157416| codons 2-399
ISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPIF
AIKKKNSNKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
EDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIV
QYMDDLYVGSDLEIGQHRTKVEELREHLLRWGLSTPDQKHQKEPPFHWMGYELHPDKWTV
QPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTEVISLTKEAEL
ELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQVYQEPFKILKTGKYARMRGAH
TNDVKQLTEAVQKVAIESIVIWGKIPKFRLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I50V, I54V, L76V, V82A, L90LM Q58E, L89V L10I, I15V, K20R, E35D, M36I, R41K, K55KR, R57RK, D60E, Q61N, I62V, L63P, A71V, I85V, Q92K, I93L G73DE
>157416| codons 1-99
PQITLWQRPIVTIKVGGQLREALLDTGADDTVLEDINLPGKWKPKIIGGVGGFVRVKEYE
NVPIEICGHKVIETVVVGPTPANIVGRNVMTKLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012