<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N V108I K20R, V35T, V60I, V90VI, K122E, D123E, I135V, T139TK, I178M, V189VI, A272P, K281R, T286P, E297R, A304E, D324DE, G335S, A355AT, M357MT, G359S, S379C, Q394L, E399D  
>157313| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKNKSVTILDVGDAYFSVPL
DEEFRKYTAFTIPSVNNEKPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVI
YQYVDDLYIGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGPKALTEVIPLTREAE
LELEENREILKEPVHGVYYDPSKELIAEIQKQGQSQWTYQIYQEPFKNLKTGKYTRTRSA
HTNDVKQLTEAVQKIATECIVIWGKTPKFKLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12V, I13V, I15V, E35D, M36I, N37D, R41K, R57K, Q61N, I64V, I72T  
>157313| codons 1-99
PQITLWQRPLVVVKVGGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVKQYD
NILVEICGHKATGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012