<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, Y115YF   L100I, K103N, Y181YC   V35VL, K122E, D123N, I135T, T200A, Q207E, L228LR, V245M, A272P, I293V, E297K, G335GD, R356K, M357MV, G359S, A360AV, K390KR L109LR
>155565| codons 2-400
ISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICTEMEKEGKISKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVRDVGDAFFSVPLD
ENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIC
QYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFRWMGYELHPDKWTV
QPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTKEAEL
ELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKVRSVH
TNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I54V, V82AS L24I, G48GR L10I, I15V, K20R, E35D, M36I, R41K, K55KR, R57K, Q61N, L63LDHV, I72T, T74S, L89M  
>155565| codons 1-99
PQITLWQRPIVTIKVGGQLREALIDTGADDTVLEDINLPGKWKPKIIRGIGGFVRVKQYD
NIVIEICGHKATGSVLVGPTPSNIIGRNMLTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012