<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67NS, K70G, L74V, Y115F   K101EQ, Y181C, G190A   P4PS, M16MT, V35I, K43E, D123E, D177E, V179IT, I195IT, T200R, R206K, H208HY, R211RK, A272P, R284K, T286A, P294A, E297A, I326V, M357MT, A360T, T377R, V381I, T386I T165TS
>154262| codons 1-400
PISSIETVPVKLKPGTDGPKVKQWPLTEEKIKALIEICTEMEEEGKISKIGPENPYNTPV
FAIKKKSSTGWRKVVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAFFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMSKILEPFRKQNPEITI
CQYMDDLYVASDLETGQHRRKIEELKQYLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLKGAKALTEVIALTAEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTRGT
HTNDVKQLTEAVQKIARESIIIWGKIPKFKLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82F, L90M V11I, L33LF, F53L L10I, I13V, K20IM, E35D, M36AV, N37HQ, R41K, R57RK, D60DE, I62V, L63P, C67L, A71IV, I72V, C95L  
>154262| codons 1-99
PQITLWQRPIITVKIGGQLMEALLDTGADDTVFEDVQLPGKWKPKMIGGIGGLVKVKQYE
QVPIEILGHKVVGTVLVGPTPFNIIGRNLMTQIGLTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012