<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L74V, L210W, T215Y   K101E, Y181C, Y188L, G190A   K20KR, V35I, T39A, K43E, E44A, L109LI, V118I, K122E, I135T, I142V, S162SN, D177E, I178M, G196GE, T200A, K201KR, E203K, Q207E, H208Y, R211K, K223Q, V245T, Q278H, A288S, I293V, E297K, G359S, A371V, A376S, T386I, K390R, E399D W24W*
>153755| codons 1-400
PISPIETVPVKLKPGMDGPRVKQ*PLTEEKIKALIEICAELEEAGKISKIGPENPYNTPV
FAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVIDVGDAYFSIPL
DEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKQNPEMVI
CQYMDDLLVASDLEIEQHRARIKELREYLWKWGFYTPDKKHQQEPPFLWMGYELHPDKWT
VQPITLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKHLCKLLRGTKSLTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRSA
HTNDVKQLTEVVQKISTESIVIWGKIPKFRLPIQKETWDA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, L76V, I84V, L90LM   L10I, T12KN, I13V, L19I, K20I, M36I, K55R, R57K, I62V, L63P, I64V, A71V, T74S, P79A, I93L  
>153755| codons 1-99
PQITLWQRPIVNVKIGGQIIEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFIRVKQYD
QVPVEICGHKVIGSVVVGATPVNVIGRNLMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012