<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74I, V75T, M184V, L210L*W, T215Y N348NI L100I, K103N   K20KR, V35T, T39A, V118I, K122E, I135V, T200A, E203ED, T240TK, V245E, A272P, E297R, Q334Y, S379G, T386V, Q394L, E399D D17DGNS, A299AT
>153753| codons 1-399
PISPIETVPVKLKPGMSGPRVKQWPLTEEKIKALTEICAELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKITDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRAKIDELRQHLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWK
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTRETE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGYGQWTYQIYQEPFKILKTGKYARMRGA
HTNDVKQLTEAVQKIATEGIVIWGKVPKFKLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A L24I, K43T Q7X, L10I, I15V, K20R, E35D, M36I, N37ND, R41K, R57K, Q61N, I62V, L63V, I72T, L89M  
>153753| codons 1-99
PQITLWXRPIVTIKVGGQLREALIDTGADDTVLEDIDLPGKWTPKIIGGIGGFVKVKQYD
NVVIEICGHKATGTVLVGPTPANIIGRNMLTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012