<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, T215F   K103N, G190A   K22KN, V35T, V60I, K101Q, K122E, I135L, E138G, I142V, I178L, T200A, V245E, A272P, K277R, T286P, I293V, E297K, V365I, K366KR, K385R, K390R, I393IM, Q394L, E399EK W398W*
>152344| codons 1-399
PISPIETVPVKLKPGMDGPKVNQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLQKNKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSLNNGTPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDLVI
YQYMDDLYVASDLEIGQHRAKIEELRQHLLRWGFFTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGPKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA
HTNDIRQLTEAVQKIATESIVIWGRTPKFRLPMLKET*K

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, E35D, M36I, P39Q, R41K, R57K, D60E, Q61D, I62V, L89M  
>152344| codons 1-99
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDINLQGKWKPKMIGGIGGFIKVKQYE
DVLIEICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012