<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T215Y   Y181C   V35K, T39A, K122P, D123E, I135T, I142V, D177E, V179I, L228LH, A272P, T286A, I293V, E297K, R358K, I380IV, T386IV, K390R, Q394L, E399D K223KEGR, W229WR
>152143| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICAEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DPEFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIII
CQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFYTPDKKHQREPPFHRMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMKGA
HTNDVKQLTEAVQKIATESVVIWGKVPKFRLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48GV, L90M   L10I, E35D, M36I, R41K, R57K, Q61N, L63G, A71V, F99FL R87RG, I93LP
>152143| codons 1-99
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIVGIGGFIKVKQYD
NIGIEICGHKVIGTVLVGPTPVNIIGGNLMTQPGCTLNL

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012