<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67~, K70R, M184V, T215F T69G, K219E K101E, Y181C, G190A A98G W88R, V106I, K122E, D123E, S162Y, L228H, K249Q, A272P, K275R, K277Q, K281KR, I293V, E297K, L301I, G335S, M357T, G359GS, T386I, K390R, E396D, E399D  
>146327| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV
FAIKKK~SGRWRKLVDFRELNKRTQDFREVQLGIPHPGGLEKKKSITVLDVGDAYFSVPL
DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIVI
CQYVDDLYVASDLEIGQHRTKIEELRQHLLRWGFFTPDEKHQKEPPFHWMGYELHPDKWT
VQPIVLPEQDSWTVNDIQKLVGKLNWASQIYPGIRVQQLCRLLRGTKALTEVVPLTKEAE
IELAENREILKEPVHGVYYDPSKDLIAEIQKQGQSQWTYQIYQEPFKNLKTGKYARTRSA
HTNDVKQLTEAVQKIATESIVIWGKIPKFRLPIQKDTWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, L90M L33F, F53L, T74P L10I, I13V, G16E, L19I, K20R, E35D, M36I, N37D, R41K, I62V, L63H, K70E, A71V, Q92QKR  
>146327| codons 1-99
PQITLWQRPIVTVKIEGQIREALLDTGADDTVFEDIDLPGKWKPKMIGGIGGLVKVRQYD
QVHIEICGHEVIGPVLVGPTPANIIGRNLMTRIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012