<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90LM   L10V, I13V, K14R, K20M, E35D, M36I, N37D, R57RK, Q61N, L63P, A71T, I72T  
>146099| codons 1-99
PQITLWQRPVVTVRIGGQLMEALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFIKVKQYD
NIPIEICGHKTTGTVLVGPTPVNIIGRNLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L210W, T215Y N348NI K103KN, V106VA   K122KE, D123E, I135T, R211K, A272P, K281KR, T286A, V292I, I293V, E297K, K311KR, E312KQ, D324E, I329V, G333E, M357T, E370EG, A371AV, S379C, K390R, I393IM, E399D P217PT
>146099| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSATVLDVGDAYFSVPL
DEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTTDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTEIVPLTKEAE
LELAENREILRQPVHGVYYDPSKELIAEVQKQEQGQWTYQIYQEPFKILKTGKYARTRGA
HTNDVKQLTGVVQKIATECIVIWGKTPKFRLPMQKETWD

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012