<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T215Y   Y181C, G190A K101N V35K, T39LS, K43KQ, V60VI, D123E, I135T, D177E, H208HY, H221Y, A272P, T286P, I293IV, E297K, V317A, M357T, G359S, V365VI, K366R, A376T, T386A, Q394L, E399D  
>142103| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICSELEQEGKISKIGPENPYNTPI
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLNKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI
CQYMDDLYVASDLEIGQHRTKIEELRQYLLRWGFYTPDKKYQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGPKALTEVVPLTKEAE
LELAENREILKEPVHGAYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTRSA
HTNDIRQLTEAVQKITTESIVIWGKAPKFKLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, V82A, L90M L33F, F53L L10V, I15V, G16E, K20R, E35D, M36I, P39S, R57K, Q61D, L63T, E65D, A71V, I72T, I93L R41EKQ
>142103| codons 1-99
PQITLWQRPVVTIKVEGQLREALLDTGADDTVFEDINLSGQWKPKLIGGIGGLIKVKQYD
DITIDICGHKVTGTVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012