<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L210W T215D K101E, Y181C, G190A   K20KR, V35T, T39A, V60VI, K64KR, T69S, W88C, K122E, D123E, I135T, T200A, R211K, D250DE, A272P, Q278H, K281R, T286A, I293V, E297M, I375V, T386V, K390R, Q394L, K395R, E399D  
>139698| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICAELEKEGKISKIGPENPYNTPI
FAIRKKDSSKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYMDDLYVASDLEIGQHRAKIEELRQHLWKWGFDTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKHLCRLLRGAKALTEVVPLTMEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA
HTNDVKQLTEAVQKVATESIVIWGKVPKFRLPILRETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54IV, V82VA, L90LIM   L10V, I13IV, I15V, G16A, K20R, E35D, M36I, N37DE, K45KR, R57K, Q61HN, L63X, G68E, A71AV, I72V, I93L  
>139698| codons 1-99
PQITLWQRPVVTVKVAGQLREALLDTGADDTVLEDIELPGRWKPRMIGGIGGFVKVKQYD
NIXIEICEHKVVGTVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012