<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, Y115F, Q151M V75I, F77L, F116Y, K219E K101E, Y181C, G190A V179F S68G, K103R, V106I, V118I, K122E, I135T, S163C, Q174R, I202V, L210F, F214L, L228H, V245L, L246I, A272P, I293V, I326V, Q332QR, Q334L, T338S, M357T, T369A, T386I V111A
>127508| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKNGTKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLEKRKSITVLDAGDAFYSIPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSPAIFQSCMTKILEPFRKRNPDIFI
CQYMDDLYVASDLEIGQHRTKVEELRQHLFRWGLTTPDEKHQKEPPFHWMGYELHPDKWT
VQPILIPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKRGLGQWSYQIYQEPFKNLKTGKYARTRGA
HTNDVKQLAEAVQKIATESIVIWGKIPKFKLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, L90M L33I, F53L, G73S L10I, I13V, K20R, E35D, M36I, R41K, K43KE, K55R, R57K, D60EK, Q61N, I62IV, L63P, A71IV, I72V, C95L G94GD
>127508| codons 1-99
PQITLWQRPIVTVKIGGQLREALLDTGADDTVIEDINLPGKWEPKMIGGIGGLVRVKQYK
NVPIEICGHKVVSTVLVGPTPANIIGRNLMTQIDLTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012