Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| HW2 | HW2_1 | Germany | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | NA |
| 2 | AZT+DDI | NA |
| 3 | D4T | NA |
| 4 | 3TC+AZT | NA |
| 5 | 3TC+AZT+SQV | NA |
| 6 | 3TC+D4T+SQV | NA |
| 7 | 3TC+D4T+RTV+SQV | NA |
| 8 | 3TC+AZT+DDI+RTV+SQV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | L10I, K20R, E35D, M36I, N37D, D60E, L63P, A71V | V77G |
| >HW2_1| codons 1-99 PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFVKVRQYE QIPIEICGHKVIGTVLGGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Walter, H | Phenotypic HIV-1 resistance correlates with treatment outcome of nelfinavir salvage therapy. | Antivir Ther, 2000 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |