Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6832 | CA21417 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV+ DDI+ AZT | 128 |
| 2 | DDI+ D4T+ APV | 38 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, I54L, L90M | L10F, L33F, N88D | I13IV, K45R, Q61E, L63P, V77I, I93L |
| >CA21417| codons 1-99 PQITLWQRPFVTVKIGGQLKEALLDTGADNTVFEEMNLPGRWKPRMIGGIGGFLKVRQYD EIPIEICGHKAIGTVLIGPTPVNIIGRDLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R | K219Q | K43Q, K64KN, T69N, S162A, I178M, T200A, E203K, Q207E, K277R, I293V |
| >CA21200| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEQEGKISKIGPENPYNTPV FAINKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPDMVI YQYMDDLYVGSDLEIGQHRAKIKELREHLLRWGFTTPDQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVVPLTEEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |