Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6839 | CA21381 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+IDV | 132 |
| 2 | D4T+DDI+EFV | 41 |
| 3 | 3TC+ABC+APV+RTV | 35 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L76V, V82A, I84V | L10I, T12TS, L19LI, N37D, K43R, R57K, I62V, L63P, A71V, I93L |
| >CA21381| codons 1-99 PQITLWQRPIVSIKIGGQIKEALLDTGADDTVLEEMDLPGRWRPKIIGGIGGFIKVKQYD QVPIEICGHKVIGTVVVGPTPANVIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, T215Y | K122E, I135V, D177DN, I178M, T200A, Q207E, V245T, E248D, A272P, K277R, E291D, E297K |
| >CA21163| codons 1-302 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPNMVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDVIPLTKEAE LE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |