Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8360 | CA21349 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC | 21 |
| 2 | SQV+ AZT+ 3TC | 115 |
| 3 | ABC+ 3TC+ NFV+ AZT | 113 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | G73S | L10LI, T12S, I13IV, L19Q, K20I, M36MI, I62IV, L63P, A71T |
| >CA21349| codons 1-99 PQITLWQRPIVSVKIGGQQIEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | E6D, K43E, E44ED, K49R, V60I, S68SG, V118I, I135T, S162D, I195IM, G196E, T200I, E203EK, Q207D, R211K, L228H, A272P, I293V, E297R |
| >CA21124| codons 1-300 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEDGKISRIGPENPYNTPI FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEMEQHRIKIKELRDHLWKWGFYTPDKKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTREAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |