<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 61

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, M184V   V106M V179D V35T, E36A, T39E, S48T, K122E, D123N, I132L, I135T, S162C, K173A, D177E, T200A, Q207A, R211K, F214L, V245Q, S251N, A272S, K275Q, K277R, R284K, T286A, E291D, V292I, I293V, P313Q, Q334H, R356K, G359T, T377M, K390R, A400T, T403S, E404D, V435A, L452T, R461K, V466I, T470N, D471E, T477A, H483Q, S519N, I526V, K527N, K530R, V531I, A554K  
>60ZA.60| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DENFRKYTAFTLPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAQNPEIDI
YQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDNWTVNDIQKLVGKLNWASQIYSGIQVRQLCKLLKGAKALTDIVPLTEEAE
LELAENREILKEQVHGVYYDPSKDLIAEIQKQGHGQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVKQLTEAVQKIAMESIVIWGKTPKFRLPIQKETWETWWSDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGAETFYVDGAANRETKTGKAGYVTDKGRQKIVSLNETTNQKAELQ
AIQLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLVNKERIYLAWVPAHK
GIGGNEQVDKLVSKGIRKVL

References
Author Title Citation
Brehm, JH Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors. Clin Infect Dis, 2012