<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 111

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N P225H I31L, V35T, E36A, T39E, S48T, K102KR, K122E, S162Y, K173A, Q174R, D177E, G196E, T200A, Q207E, R211K, L228R, V245Q, A272S, K281R, T286A, E291D, V292I, I293V, D324E, Q334D, G335D, Y342F, A355T, R356K, M357R, G359A, T377M, I382T, K390R, A400T, E404D, V435A, A437V, K454R, S468P, D471E, T477A, H483Q, V493A, S519N, K527N, K530R, A534S, A554S A508AV
>49ZA.108| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRNKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRARNPEIVI
YQYVDDLYVGSDLEIEQHRAKIEELREHLLKWGFTTPDKKHQKEHPFRWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCRLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGDDQWTYQIFQEPFKNLKTGKYTKRRAA
HTNDVKQLTEAVQKIAMESIVTWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGVETFYVDGAANRETKLGRAGYVTDRGRQKVVPLTETTNQKAELQ
AIQLALQDSGLEANIVTDSQYALGIIQVQPDKSESELVNQIIEQLINKERVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Brehm, JH Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors. Clin Infect Dis, 2012