<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 45

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   V106M, M230L   V35T, E36A, T39E, S48T, K122E, D123N, Q174N, T200A, Q207N, R211K, F214L, V245M, A272P, K275Q, K277R, Q278H, E291D, V292I, I293V, P294T, I329L, Q334D, K347R, R356K, G359T, A376T, T377L, K390R, A400T, E404D, W410C, V435A, E449D, L452M, R461K, V466I, S468T, T470N, D471E, T477A, H483Q, S519N, K527N, K530R, V531I, A534S, A554S  
>42ZA.36| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKNNPDIVI
YQYVDDLYVGSDLEIGQHRAKIEELRNHLLKWGLTTPDKKHQKEPPFLWLGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIQVRHLCKLLRGTKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGDGQWTYQIYQEPFRNLKTGKYAKMRTA
HTNDVKQLTEAVQKITLESIVIWGKTPKFRLPIQKETWETWWTDYWQATCIPEWEFVNTP
PLVKLWYQLEKEPIAGAETFYVDGAANRDTKMGKAGYVTDKGRQKIVTLNETTNQKAELQ
AIQLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKERIYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Brehm, JH Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors. Clin Infect Dis, 2012