<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 99

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V V75VI K101KE, K103N, G190A   K20KR, V35T, E36A, T39E, S48T, V60I, K102KN, K122E, D123G, I132IL, I135IM, S162A, K166R, K173A, D177E, I178M, T200A, Q207R, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, Q334D, G335D, R356K, M357R, G359T, V365VI, T377Q, K390R, A400I, E404D, V435A, L452M, V466I, V467T, T470S, D471E, T477A, H483Q, L491S, E514D, L517I, S519N, A534S, V548I, A554S  
>41ZA.96| codons 1-560
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLENNKSVTVLDVGDAYFSVPL
DEGFRKYTAFTLPSMNNETPGIRYQYNVLPQGWKGSPAIFQASMTRILEPFRAQNPEMVI
YQYVDDLYVASDLEIGQHRAKIEELRRHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDDQWTYQIYQEPFKNLKTGKYAKRRTA
HTNDIKQLTEAVQKIAQESIVIWGKTPKFRLPIQKETWEIWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGAETFYVDGAANRETKMGKAGYVTDRGRQKITSLSETTNQKAELQ
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSDSEIVNQIIEQLIKKEKVYLSWVPAHK
GIGGNEQIDKLVSSGIRKVL

References
Author Title Citation
Brehm, JH Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors. Clin Infect Dis, 2012