<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 17

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
      V179D V35T, E36A, T39D, S48T, W88C, K122E, D123G, I135T, E138S, K173A, Q174K, D177E, T200A, Q207E, F214L, V245H, D250E, K277R, T286A, E291D, V292I, I293V, Q334NY, G335D, R356K, G359T, T369A, T377L, T386I, K390R, A400I, E404D, E413D, V435A, T470S, D471E, H483Q, L484I, L491S, V496I, S519N, Q524L, K530R, A534S, A554K, K558R  
>35ZA.84| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSTNNSTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIDI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIHLPEKESWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGYDQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVKQLAEAVQKIALESIVIWGKIPKFRLPIQKETWEIWWTDYWQATWIPDWEFVNTP
PLVKLWYQLEKEPIAGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLSETTNQKTELQ
AIQIALQDSGSEVNIITDSQYALGIIQAQPDKSESELVNQIIELLIKKERVYLSWVPAHK
GIGGNEQVDKLVSKGIRRVL

References
Author Title Citation
Brehm, JH Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors. Clin Infect Dis, 2012