Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8384 | CA21331 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI+IDV+NVP | 82 |
| 2 | D4T+DDI+IDV+RTV | 89 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N88S, L90M | Q58E | L10I, I15V, K20T, E35D, M36I, I62V, L63P, A71T, I85IV |
| >CA21331| codons 1-99 PQITLWQRPIVTIKVGGQLTEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVREYD QVPIEICGHKTIGTVLVGPTPVNIVGRSLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, T215F | D67G, K219E | Y181C | V35M, K49R, S68G, D121H, K122E, D123S, I135T, Q174R, P176T, I178M, T200A, R211K, D218E, V245Q, L260I, K277R |
| >CA21113| codons 1-283 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICTEMEKEGKISRIGPENPYNTPV FAIKKKGGTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNTDMVI CQYMDDLYVGSDLEIGQHRAKIEELRQHLLKWGFFTPEEKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKIVGKLNWASQIYAGIKVRQLCKLL |
References
| Author | Title | Citation |
| Rhee, SY | Genotypic predictors of human immunodeficiency virus type 1 drug resistance. | PNAS, 2006 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |