<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 43

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V N348NI K103N, Y181C   V35T, E36A, T39E, K49KR, K173I, Q174K, T200E, E203G, Q207E, R211K, V245Q, D250E, S251C, A272P, T286V, V292I, I293V, I329L, Q334D, G335D, R356K, M357KR, G359T, A360T, V365I, E370D, A376S, T377M, K385KR, K390R, E399D, A400M, E404D, E432D, I434M, V435T, A437V, L452I, K454R, S468T, D471E, H483Q, L491S, S519N, K530R, A534S, A554N  
>26ZA.36| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPDIVI
CQYVDDLYVGSDLEIGQHREKIGELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKECWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGVKALTEIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGDDQWTYQIYQEPFKILKTGKYAKRRTT
HTNDIKQLTDAVQKISMESIVIWGRTPKFRLPIQKETWDMWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKDPMTGVETFYVDGAANRETKIGRAGYVTDRGRQKVVTLTETTNQKTELQ
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK
GIGGNEQVDKLVSNGIRKVL

References
Author Title Citation
Brehm, JH Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors. Clin Infect Dis, 2012