<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 24

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    G190A   E6D, V35K, T39E, E40D, K122E, D123N, I135T, S162C, K173T, E194N, T200A, Q207E, R211K, A272P, L279T, T286A, E291D, V292I, I293V, V317A, I329V, Q334H, G335D, R356K, G359T, T369A, A371T, T377L, K390R, A400T, E404D, V435A, G436E, V466I, T470N, D471E, T477A, H483Q, L491S, S519N, K527N, E529D, K530R, V531I, A534S, A554S  
>17ZA.24| codons 1-560
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALKEICEDMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRTQNPDIVI
YQYMDDLYVASDLNIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQTCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGAYYDPSKDLIAEVQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVKQLAETVQKIALESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAEAETFYVDGAANRETKLGKAGYVTDRGRQKIVSLNETTNQKAELQ
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKDRIYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Brehm, JH Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors. Clin Infect Dis, 2012